厦门大学生命科学学院导师介绍:徐庆妍
作者:聚创厦大考研网-小厦老师
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发布时间: 2018-09-08 11:29
微信号: H17720740258
徐庆妍 XU Qingyan, Ph.D.
副教授硕士生导师
电 话:+86-592-2180328
E-mail: xuqingyan@yahoo.com
1992年,华西医科大学药学院(今四川大学华西药学院),学士学位;
1995年,华西医科大学药学院(今四川大学华西药学院)天然药化专业,硕士学位;
2004年,厦门大学,理学博士学位;
2006年至2007年,法国斯特拉斯堡市路易-巴斯德大学药学院,博士后;
1995年至今,厦门大学生命科学学院,助教、讲师、副教授。
1992, B. Sc. West China University of Medical Science
1995, M. Sc. West China University of Medical Science
2004, Ph. D. Xiamen University
2006-2007, Postdoctoral Fellow, Louis-Pasteur University, Strasbourg, France
1995-present, Assistant Professor, Associate Professor, School of Life Science, Xiamen University
研究领域(Research Area)
微生物药物学。从事与微生物活性代谢产物相关的研究。除抗菌、抗肿瘤活性外,目前主要从事抑制肿瘤坏死因子-α (TNF-α)活性的小分子化合物的研究,希望可以找到阻断TNF-α导致细胞坏死的信号通路的药物。
Microbial Pharmacology. The main research area lies in Microbial Pharmacology. More than antibacterial and antitumor activities, we focus on the research of compounds with anti-TNF-α activity. We hope to find inhibitors that block the necrosis signaling pathway of TNF-α from microorganisms.
代表性论文(Selected Publications)
1. Liu J L., Hu Z Y., Huang Y J., Zheng Z H, Xu Q Y*. Aspochalasin U, a moderate TNF-α inhibitor from Aspergillus sp[J]. Journal of Antibiotics. 2012, 65 : 49-52.
2. Liu J L, Hu Z Y, Xu Q Y*. 3 '-(3-Hydroxyphenyl)-4-methylspiro benzo e 1,4 diazepine-3,2 '-oxirane -2,5(1H, 4H)-dione[J]. Acta Crystallographica Section E - Structure Reports Online, 2011, 67: O1670 - U1532.
3. Zimmermann M, Atmanene C, Xu Q Y, Fouillen L, Van Dorsselaer A, Bonnet D, Marsol C, Hibert M, Sanglier-Cianferani S, Pigault C, McNamara LK, Watterson DM, Haiech J*, Kilhoffer MC. Homodimerization of the Death-Associated Protein Kinase Catalytic Domain: Development of a New Small Molecule Fluorescent Reporter[J]. PLoS ONE, 2010, 5(11). E14120.
4. Zhan Y Y, Du X P, Chen H Z, Liu J J, Zhao B X, Huang D H, Li G D, Xu Q Y, Zhang M Q, Weimer B C, Chen D, Cheng Z, Zhang L R, Li Q X, Li S W, Zheng Z H, Song S Y, Huang Y J, Ye Z Y, Su W J, Lin S C, Shen Y M, Wu Q*. Cytosporone B is an agonist for nuclear orphan receptor Nur77 [J]. Nature Chemical Biology, 2008, 4(9):548-556.
5. Xu Z, Xu Q Y, Zheng Z H, Huang Y J*. Kribbella amoyensis sp. nov., isolated from the rhizosphere soil of a pharmaceutical plant, Typhonium giganteum Engl [J]. International Journal of Systematic and Evolutionary Microbiology, 2011. PMID: 21705443.
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