厦门大学化学化工学院分析科学研究所导师介绍：吴川六​

吴川六

课题组主页：http://chlwu.xmu.edu.cn
邮箱：chlwu@xmu.edu.cn
办公室：化学楼535
电话：0592-2183206

个人简历：
博士（厦门大学，2005-2010）
学士（厦门大学，2001-2005）
研究助理（新加坡国立大学，2008-2009）
博士后（瑞士苏黎世联邦理工学院，2010-2012） 

ETH Fellow（2010）
中组部第五批“青年千人”计划（2013）

研究兴趣：
多肽分子探针；荧光探针；多肽/蛋白递送系统；蛋白质–多肽分子相互作用；生物分子识别机制 近期主要代表论著：

1. Yunyang Ling,^‡ Jing Ren,^‡ Tao Li, Yibing Zhao and Chuanliu Wu*, POEGMA-Based Disulfide-Containing Fluorescent Probes for Imitating and Tracing Noninternalization-Based Intracellular Drug Delivery, Chem. Commun., 2016,52, 4533−4536.
2. Yiwu Zheng, Linxiang Zhai, Yibing Zhao, and Chuanliu Wu*, Orthogonal Cysteine-Penicillamine Disulfide Pairing for Directing the Oxidative Folding of Peptides, J. Am. Chem. Soc., 2015, 137, 15094−15097.
3. Yujie Li,^‡ Tao Li,^‡ Jinghui Wang, Xiaojia Bao, Yibing Zhao, and Chuanliu Wu*, Multivalent Peptides Displayed on OEGMA-based Copolymers for the Modulation of Protein-Protein Interactions, Polym. Chem., 2015, 6, 7862−7870.
4. Yaqi Chen,^‡ Chaoqiong Yang,^‡ Tao Li, Miao Zhang, Yang Liu, Marc A. Gauthier, Yibing Zhao, and Chuanliu Wu*, The Interplay of Disulfide Bonds, α-Helicity, and Hydrophobic Interactions Leads to Ultrahigh Proteolytic Stability of Peptides, Biomacromolecules, 2015, 16, 2347−2355.
5. Linxiang Zhai, Jingjing Liang, Xiangqun Guo, Yibing Zhao, and Chuanliu Wu*, Extraordinary Modulation of Disulfide Redox-Responsiveness by Cooperativity of Twin-Disulfide Bonds, Chem. Eur. J., 2014, 20, 17507−17514.
6. Chuanliu Wu,^‡ Shuo Wang,^‡ Lorine Brülisauer, Jean-Christophe Leroux, and Marc A. Gauthier*, Broad Control of Disulfide Stability through Microenvironmental Effects and Analysis in Complex Redox Environments,Biomacromolecules, 2013, 14, 2383−2388.
7. Chuanliu Wu, Jean-Christophe Leroux,* and Marc A. Gauthier*, Twin Disulfides for Orthogonal Disulfide Pairing and the Directed Folding of Multicyclic Peptides, Nature Chem., 2012, 4, 1044−1049.
8. Chuanliu Wu, Cristina Belenda, Jean-Christophe Leroux, and Marc A. Gauthier*, Interplay of Chemical Microenvironment and Redox Environment on Thiol–Disulfide Exchange Kinetics, Chem. Eur. J., 2011, 17, 10064−10070.