作者:聚创厦大考研网-小厦老师 点击量: 1387 发布时间: 2018-09-11 14:55 微信号: H17720740258
李庆顺 Qingshun Quinn Li | 教授
办公地点院长
办公电话0592-2189836
邮箱liqq@xmu.edu.cn
履历
理学学士:植物学,厦门大学生物系,1983
理学硕士:生化遗传学,厦门大学生物系,1986
理学博士:植物生理学、生化与分子生物学,美国肯塔基大学,1995
博士后:植物分子生物学及生化,美国肯塔基大学,1995-1996
1983 Bachelor of Science, Plant science, Xiamen University, Xiamen, China.
1986 Master of Science, Biochemical Genetics, Xiamen University, Xiamen, China.
1995 Ph.D., Molecular Biology and Biochemistry, University of Kentucky, Lexington, Kentucky, USA.
1995-1996 Postdoctoral Fellow, Molecular Biology and Biochemistry, University of Kentucky, Lexington, Kentucky, USA.
现任(2012-至今):厦门大学环境与生态学院,院长,教授。
2010-2015:正教授(终身教授),美国迈阿密大学生物系(原植物学系), 俄亥俄洲牛津市。
2007-2010:副教授,迈阿密大学植物学系。
2001-2007: 助理教授,迈阿密大学植物学系
1996-2001:科学研究员(Scientist), 课题负责人,美国肯塔基大学烟草研究发展中心
1995-1996:博士后,美国肯塔基大学,植物分子生物学及生物化学
1991-1995:研究助理,美国肯塔基大学植物生理学,分子生物学及生物化学方向
1989-1991:讲师,厦门大学生物系
1986-1988:助教,厦门大学生物系
2012-present, Dean, College of the Environment and Ecology, Xiamen University, Xiamen, Fujian, China
2010-2015 Professor, Botany (now Biology) Department, Miami University, Oxford, Ohio, USA
2007-2010 Associate Professor, Botany Department, Miami University, Oxford, Ohio.
2001-2007 Assistant Professor, Botany Department, Miami University, Oxford, Ohio.
1996-2001 Staff Scientist III and Principal Investigator, Kentucky Tobacco Research and Development Center, University of Kentucky, Lexington, Kentucky
1995-1996 Postdoctoral Scholar, Plant Physiology/Biochemistry/Molecular Biology Program, University of Kentucky, Lexington, Kentucky.
1991-1995 Research Assistant, University of Kentucky, Plant Physiology/Biochemistry/ Molecular Biology Program, Lexington, Kentucky.
1988-1991 Lecturer, Department of Biology, Xiamen University, Xiamen, Fujian, P. R. China.
1986-1988 Assistant Professor, Department of Biology, Xiamen University, Xiamen, Fujian, P. R. China.
研究方向
分子生态学:植物对环境适应性的分子生物学、组学基础
植物mRNA多聚腺苷化的分子生物学,转录组学,遗传学, 生物信息学研究
Molecular ecology: the molecular basis of plant adaptation to the environment
Plant mRNA polyadenylation studies using molecular biology, transcriptomics, genetics, and bioinformatics tools
代表性论文
Congting Ye, Yuqi Long, Guoli Ji, Q. Quinn Li*, Xiaohui Wu*. 2018. APAtrap: identification and quantification of alternative polyadenylation sites from RNA-seq data. Bioinformatics, in press. DOI:10.1093/bioinformatics/bty029
Neza Repar, Li Hao, Jose S. Aguilar, Q. Quinn Li, Drobne Damjana, and Yiling Hong*. 2018. Silver nanoparticles induced neurotoxicity in neuron and astrocyte network derived from human embryonic stem cells. Nanotoxicology, in press. DOI: 10.1080/17435390.2018.1425497
Liwei Hong, Wenyue Su, Yuanye Zhang, Congting Ye, Yingjia Shen, Q. Quinn Li*. 2018. Transcriptome profiling during mangrove viviparity in response to abscisic acid. Scientific Reports, 8:770. DOI:10.1038/s41598-018-19236-x.
Liwei Hong, Congting Ye, Juncheng Lin, Haihui Fu, Xiaohui Wu and Q. Quinn Li*. 2018. Alternative polyadenylation is involved in auxin-based plant growth and development. Plant Journal, 93:246-258. DOI:10.1111/tpj.13771.
Luzhen Chen*, Wenqing Wang, Qingshun Q. Li, Yihui Zhang, Shengchang Yang, Michael J. Osland, Jinliang Huang, and Congjiao Peng. 2017. Mangrove species’ responses to winter air temperature extremes in China.Ecosphere, 8(6): e01865. DOI: 10.1002/ecs2.1865
Juncheng Lin, Ruqiang Xu, Xiaohui Wu, Yingjia Shen and Qingshun Q. Li*. 2017. Role of Cleavage and Polyadenylation Specificity Factor 100: Anchoring Poly(A) Sites and Terminating Transcription in Arabidopsis.Plant Journal, 91:829–839. DOI: 10.1111/tpj.13611.
Cheng Guo, Matthew Spinelli, Congting Ye, Qingshun Q. Li* and Chun Liang*. 2017. Genome-Wide Comparative Analysis of Miniature Inverted Repeat Transposable Element in 19 Arabidopsis thaliana Accessions. Scientific Reports, 7:2634. DOI: 10.1038/s41598-017-02855-1.
Qingshun Q. Li*, Zhaoyang Liu, Wenjia Lu and Man Liu. 2017. Interplay between Alternative Splicing and Alternative Polyadenylation Defines the Expression Outcome of the Plant Unique OXIDATIVE TOLERANT-6 Gene.Scientific Reports, 7:2052. DOI: 10.1038/s41598-017-02215-z
Kristopher J. L. Irizarry*, Adam Chan, Derek Kettle, Steven Kezian, Dominic Ma, Louis Palacios, Qingshun Q. Li, Calvin L. Keeler and Yvonne Drechsler. 2017. Bioinformatics Analysis of Chicken miRNAs Associated with Monocyte to Macrophage Differentiation and Subsequent IFNg Stimulated Activation. MicroRNA. 6:1-19. DOI:10.2174/2211536605666161129122803.
Haihui Fu, Dewei Yang, Wenyue Su, Liuyin Ma, Yingjia Shen, Guoli Ji, Xinfu Ye, Xiaohui Wu, Qingshun Q. Li *. 2016. Genome-wide dynamics of alternative polyadenylation in rice. Genome Research. 26(12): 1753-1760. DOI: 10.1101/gr.210757.116.
周晓旋, 蔡玲玲, 傅梅萍, 洪礼伟, 沈英嘉, 李庆顺*. 红树植物胎生现象研究进展. 植物生态学报. 2016, 40(12): 1328-1343. Xiao-xuan Zhou, Ling-ling Cai, Mei-ping Fu, Li-wei Hong, Ying-jia Shen, Qingshun Q. Li*, 2016. Progress in the Studies of Vivipary on Mangrove Plants. Chinese Journal of Plant Ecology 40(12):1328-1343. (In Chinese with English abstract) Doi:10.17521/cjpe.2016.0087.
Xiaohui Wu*, Yumin Zhang, Qingshun Q. Li*. 2016. PlantAPA: a portal for visualization and analysis of alternative polyadenylation in plants. Frontiers in Plant Science. 7:889. DOI: 10.3389/fpls.2016.00889.
Cheng Guo, Matthew Spinelli, Man Liu, Qingshun Q. Li* and Chun Liang*. 2016. A Genome-wide Study of "Non-3UTR" Polyadenylation Sites in Arabidopsis thaliana. Scientific Report. 6:28060; DOI: 10.1038/srep28060.
Dewei Yang, Xinfu Ye*, Xianghua Zheng, Chaoping Cheng, Ning Ye, Libin Lu, Fenghuang Huang, Qingshun Q. Li*. 2016. Identification and fine mapping of lemma-distortion1, a single recessive gene playing an essential role in the development of lemma in rice. J. Agricultural Science. DOI:10.1017/S0021859615000866.
Xiaohui Wu*, Yong Zeng, Jinting Guan, Guoli Ji, Rongting Huang and Qingshun Q. Li*. 2015. Genome-wide characterization of intergenic polyadenylation sites redefines gene spaces in Arabidopsis thaliana. BMC Genomics. 16:511.
Guoli Ji, Jinting Guan, Yong Zeng, Qingshun Q. Li and Xiaohui Wu*. 2015. Genome-wide identification and predictive modeling of polyadenylation sites in eukaryotes. Briefings in Bioinformatics.16(2): 304-313. DOI: 10.1093/bib/bbu011.
Guoli Ji, Lei Li, Qingshun Q. Li, Xiangdong Wu, Jingyi Fu, Xiaohui Wu*. 2015. PASPA: a web server for mRNA poly(A) site predictions in plants and algae. Bioinformatics. 31(10): 1671-3.
Jinting Guan, Jingyi Fu, Mingcheng Wu, Longteng Chen, Guoli Ji, Qingshun Q. Li, Xiaohui Wu*. 2015. VAAPA: A web platform for visualization and analysis of alternative polyadenylation. Comput Biol Med. 57:20-25.
Man Liu, Ruqiang Xu, Carrie Merrill, Liwei Hong, Carol Von Lanken, Arthur G. Hunt* and Qingshun Q. Li*. 2014. Integration of developmental and environmental signals via a polyadenylation factor in Arabidopsis. PloS One. 9: e115779. DOI:10.1371/journal.pone.0115779.
William C Ray*, Samuel L Wolock, Nicholas W Callahan, Min Dong, Qingshun Q. Li, Chun Liang, Thomas J. Magliery and Christopher W. Bartlett. 2014. Addressing the unmet need for visualizing Conditional Random Fields in Biological Data. BMC Bioinformatics. 15:202.
Xiaohui Wu, Bobby Gaffney, Arthur G. Hunt*, and Qingshun Q. Li*. 2014. Genome-wide determination of poly(A) sites in Medicago truncatula: evolutionary conservation of alternative poly(A) site choice. BMC Genomics. 15:615. DOI: 10.1186/1471-2164-15-615.
Zhixin Zhao, Xiaohui Wu, Praveen Kumar Raj Kumar, Min Dong, Guoli Ji, Qingshun Q. Li* and Chun Liang*. 2014. Bioinformatics analysis of alternative polyadenylation in green alga Chlamydomonas reinhardtii using transcriptome sequences from three different sequencing platforms. Genes Genomics Genetics (G3). 4:871-883. DOI: 10.1534/g3.114.010249.
Liuyin Ma, Pratap Kumar Pati, Man Liu, Qingshun Q. Li* and Arthur G. Hunt*. 2014. High throughput characterizations of poly(A) site choice in plants. Methods. 67:74-83.
Liuyin Ma, Cheng Guo and Qingshun Q. Li*. 2014. Role of alternative polyadenylation in epigenetic silencing and antisilencing. Proc. Nat. Acad. Sci. USA. 111:9-10. DOI: 10.1073/pnas.1321025111.
Denghui Xing, Yajun Wang, Ruqiang Xu, Xinfu Ye, Dewei Yang, Qingshun Q. Li*. 2013. The Regulatory Role of Pcf11-Similar-4 (PCFS4) in Arabidopsis Development by Genome-Wide Physical Interactions with Target Loci. BMC Genomics. 14:598. DOI:10.1186/1471-2164-14-598.
Guoli Ji*, Yong Zeng, Jinting Guan, Qingshun Q. Li, Congting Ye, Yunlong Liu. 2013. Recent advances in mathematical modeling and simulation of DNA replication process. Current Bioinformatics. 8:591-602. DOI: 10.2174/15748936113088880005.
Patrick E. Thomas, Xiaohui Wu, Man Liu, Bobby Gaffney, Guoli Ji, Qingshun Q. Li and Arthur G. Hunt*. 2012. Genome-wide control of polyadenylation site choice by CPSF30 in Arabidopsis. Plant Cell. 24: 4376-4388. DOI:10.1105/tpc.112.096107.
Arthur G. Hunt, Denghui Xing*, Qingshun Q. Li*. 2012. Plant polyadenylation factors: conservation and variety. BMC Genomics. 13:641. DOI: 10.1186/1471-2164-13-641.
Hongwei Zhao, Jun Zheng, Qingshun Q. Li*. 2011. A novel plant in vitro assay system for pre-mRNA during 3’-end formation. Plant Physiology. 157:1546-1554. DOI: 10.1104/pp.111.179465.
Yingjia Shen, R. C. Venu, Kan Nobuta, Xiaohui Wu, Varun Notibula, Caghan Demirci, Blake C Meyers, Guo-Liang Wang, Guoli Ji, Qingshun Q. Li*. 2011. Transcriptome Dynamics Through Alternative Polyadenylation in Developmental and Environmental Responses in Plants Revealed by Deep Sequencing. Genome Research. 21:1478-1486. DOI: 10.1101/gr.114744.110.
Xiaohui Wu, Man Liu, Bruce Downie, Chun Liang, Guoli Ji, Qingshun Q. Li*, Arthur Hunt*. 2011. Genome-wide landscape of polyadenylation in Arabidopsis provides evidence for extensive alternative polyadenylation. Proc. Nat. Acad. Sci. USA. 108:12533–12538. DOI: 10.1073/pnas.1019732108.
Jianti Zheng, Denghui Xing, Xiaohui Wu, Diana Kroll, Yingjia Shen, Guoli Ji, Qingshun Q. Li*. 2011. Ratio-based analysis of differential mRNA processing and expression of a polyadenylation factor mutant pcfs4 using Arabidopsis tiling microarray. PLoS One. 6:e14719. DOI: 10.1371/journal.pone.0014719.
Denghui Xing, Qingshun Q. Li*. 2011. Alternative polyadenylation and gene expression regulation in plants. Willey Interdisciplinary Reviews-RNA. 2:445-458. (Invited review) DOI: 10.1002/wrna.59.
开设课程
环境与生态学科入门
分子生物学基础
遗传与进化
分子生态学(研究生)
环境与生态组学(研究生)
Introduction of Environmental Study and Ecology
Introductory Molecular Biology
Genetics and Evolution
Molecular Ecology (graduate students)
Ecological and Environmental Omics (Graduate students)
科研课题
红树植物基因组、转录组、基因表达与抗逆适应性研究
植物mRNA选择性多聚腺苷化及其与环境适应性的关系
Genomics of mangrove plants, and the relationship between their gene expression and adaptation.
Plant mRNA alternative polyadenylation and gene expression regulation in responding to environmental stresses.
荣誉奖励
美国迈阿密大学杰出学者 (2012)
美国迈阿密大学2011年度最佳研究者,Sigma Xi – 科学研究协会,迈阿密大学分会。
美国肯塔基大学植物与土壤科学系,杰出校友,2014.
福建省引进高层次创新创业人才(2012)
厦门市双百计划创新人才(2013)
Distinguished Scholar, Miami University 2012.
Researcher of the Year award, Sigma Xi – Scientific Research Society, 2011, Miami University Chapter.
Distinguished Alumnus Award, Department of Plant and Soil Sciences, University of Kentucky, 2014.
Fujian Provincial Hundred Talents Plan Awardee, 2012.
Xiamen Hundred Talents Plan Awardee, 2013.
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