厦门大学生命科学学院导师介绍：王义权
作者：聚创厦大考研网-小厦老师
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发布时间： 2018-09-08 10:47
微信号： H17720740258
王义权 WANG Yi-Quan, Ph.D.
教授，博士生导师
发育遗传与比较基因组
（Developmental Genetics and Comparative Genomics）
课题组长
E-mail：wangyq@xmu.edu.cn
安徽师范大学学士（1982）；
陕西师范大学动物学助教班（1985）；
南京师范大学博士（1995）；
中国药大学博士后（1997）；
香港科技大学访问学者（1998）；
南京师范大学教授、博导（1999）；
美国德克萨斯大学访问教授（2000）；
美国辛辛那提大学访问学者（2001）；
2002年至今，厦门大学生命科学学院，教授。
BSc, AnhuiNormal University (1982);
Graduated program, ShaanxiNormalUniversity (1985);
Ph. D., NanjingNormalUniversity (1995);
Postdoctoral Fellow, China Pharmaceutical University (1997);
Visiting Scholar, Hong KongUniversity of Science & Technology (1998);
Professor, NanjingNormalUniversity (1999);
Visiting Professor, TexasUniversity (Houston), USA (2000);
Visiting Scientist, University of Cincinnati, USA (2001);
Professor, XiamenUniversity (2002).
研究领域
文昌鱼是现存生物中与脊椎动物最相似的无脊椎动物，因此是研究脊椎动物起源及其胚胎发育机制的理想模型。我们课题组主要运用基因敲除、转基因、显微注射、原位杂交、扫描电镜等试验手段，研究文昌鱼早期胚胎发育机制，特别是体轴建立机制，以期对脊椎动物器官起源与发育机制有更深入的理解。
Research Area
Among the living invertebrates, amphioxus shows most similarities with vertebrates in respect to either body structure, developmental process, or genome content, which makes amphioxus an ideal model organism for studying developmental and evolutionary mechanisms of vertebrate embryogenesis. We are using methods including gene knockout, transgene, microinjection, whole-mount in situ hybridization and scanning electron microscope to dissect the molecular mechanisms of amphioxus embryogenesis, aiming to illustrate how the morphological and developmental complexity of vertebrates has evolved.
代表性论文(Selected Publications)
1. Li G, Liu X, Xing CF, Zhang HY, Shimeld SM, Wang YQ*. (2017) Cerberus-Nodal-Lefty-Pitx signaling cascade controls left-right asymmetry in amphioxus. PNAS, 14(114): 3684–3689
2. Li G, Wang J, Yuan L, Wang H, Wang YQ*. (2015) A simple method for selecting spawning-ready individuals out from laboratorial cultured amphioxus population. Journal of experimental zoology, 324(7):629-635.
3. Feng J, Li G, Liu X, Wang J, Wang YQ*. (2014) Functional analysis of the promoter region of amphioxus beta-actin gene: a useful tool for driving gene expression in vivo. Mol Biol Rep. 41:6817–6826
4. Li G, Feng J, Lei Y, Wang J, Wang H, Shang LK, Liü DT, Zhao H, Zhu Y and Wang YQ*. (2014) Mutagenesis at specific genomic loci of amphioxus Branchiostoma belcheri using TALEN method. Journal of Genetics and Genomics. 41(4):215-219
5. Liü X, Li G, Feng J, Yang X, Wang YQ*. (2013) An efficient microinjection method for unfertilized eggs of Asian amphioxus Branchiostoma belcheri. Dev Genes Evol. 223:269-278
6. Li WY, Zhong J, Wang YQ*. 2013. Genetic diversity and population structure of two lancelets along the coast of China. Zoological Science. 30(2):83-91
7. Qian GH, Li G, Chen X, Wang YQ*. (2013) Characterization and embryonic expression of four amphioxus Frizzled genes with important functions during early embryogenesis. Gene Expr Patterns. 13(8):445-453
8. Li G, Shu ZH and Wang YQ*. (2013) Year-round reproduction and induced spawning of Chinese amphioxus, Branchiostoma Belcheri, in laboratory. PLoS ONE.8(9): e75461
9. Xu QH, Li G, Cao LX, Wang ZJ, Ye H, Chen XY, Yang X, Wang YQ* and Chen LB. (2012) Proteomic characterization and evolutionary analyses of zona pellucida domain-containing proteins in the egg coat of the cephalochordate, Branchiostoma belcheri. BMC Evolutionary Biology. 12:239
10.Li G, Yang X, Shu ZH, Chen XY and Wang YQ*. (2012) Consecutive spawnings of Chinese amphioxus, Branchiostoma belcheri, in captivity. PLoS ONE. 7(12): e50838
11.Li DL, Li G, Wang KR, Liu X, Li W, Chen XY, Wang YQ*. (2012) Isolation and functional analysis of the promoter of the amphioxus Hsp70a gene. Gene. 510(1):39-46
12.Sun Y, Zhang QJ, Zhong J, Wang YQ*. (2010) Characterization and expression of AmphiBMP3/3b gene in amphioxus Branchiostoma japonicum. Develop. Growth Differ., 52:157-167
13.Li G, Zhang J, Sun Y, Wang H, Wang YQ*. (2009) The evolutionarily dynamic IFN-inducible GTPase proteins play conserved immune functions in vertebrates and cephalochordates. Mol Biol Evol. 26 (7):1619-1630.
14.Li G, Zhang QJ, Zhong J, Wang YQ*. (2009) Evolutionary and functional diversity of green fluorescent proteins in cephalochordates. Gene. 446(1):41-49.
15.Li G, Shi P and Wang YQ*. (2007) Evolutionary dynamics of the ABCA-chr17q24 cluster genes in vertebrates. Genomics. 89 (3) 385–391.
16.Wang W, Zhong J, Su B, Zhou Y, Wang YQ*. (2007) Comparison of Pax1/9 locus reveals 500-Million-Year-Old syntenic block and evolutionary conserved non-coding regions. Mol Biol Evol. 24: 784-791
17.Li G, Zhang QJ, Ji ZL, Wang YQ*. (2007) Origin and evolution of vertebrate ABCA genes: A story from Amphioxus. Gene. 405 (1-2):88-95.
18.Zhang QJ, Li G, Sun Y, Wang YQ*. (2009) Chromosome Preparation and Preliminary Observation of Two Amphioxus Species in Xiamen. Zoological Research. 30(2): 131?136
参加学术团体的情况（Professional Service）
中国遗传学会理事；福建省遗传学会副理事长；福建省动物学会常务理事；
《遗传》,《动物学研究》编委。
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