厦门大学化学化工学院有机化学研究所导师介绍：唐果

  唐果
  地址: 厦门大学化学化工学院化学系卢嘉锡楼816 （361005）
  电话：18030301305, 13015916658
  E-mail: t12g21@xmu.edu.cn
  个人简历：
  2010－2011   博士后研究 清华大学（新竹）化学系
  2009－           副教授        厦门大学化学化工学院化学系有机所
  2004－2009   助理教授     厦门大学化学化工学院化学系有机所
  2001－2004   攻读博士     厦门大学化学化工学院有机化学
  1998－2001   攻读硕士     四川大学轻纺与食品学院
  1994－1998   攻读学士     四川大学轻纺与食品学院
  研究兴趣：
  磷化学，含磷阻燃剂，杂环化学，精细化学品的高效合成
  近期主要代表论著：
  2017 年研究论文：
  (1)
  Yuzhen Gao, Pengbo Zhang, Ze Ji, Guo Tang,* and Yufen Zhao. Copper-Catalyzed Cascade Radical Addition?Cyclization Halogen Atom Transfer between Alkynes and Unsaturated αHalogenocarbonyls. ACS Catal., 2017, 7, 186.
  (2)
  Pengbo Zhang, Yuzhen Gao, Su Chen, Guo Tang,* and Yufen Zhao. Direct synthesis of 2-sulfonated 9H-pyrrolo[1,2-a] indoles via NaI-catalyzed cascade radical addition/ cyclization/isomerization. Org. Chem. Front., 2017, 4, 1350.
  (3)
  Guozhang Lu, Binzhou Lin, Yuzhen Gao, Jianxi Ying, Guo Tang,* and Yufen Zhao. Mn(OAc)3-Mediated Synthesis of 3-Phosphonyldihydrofurans from β-Ketophosphonates and Alkenes. Synlett, 2017, 28, 724.
  (4)
  Pengbo Zhang, Jianxi Ying, Guo Tang,* and Yufen Zhao. Phosphinodifluoroalkylation of alkynes using P(O)H compounds and ethyl difluoroiodoacetate. Org. Chem. Front., 2017, 4, DOI: 10.1039/c7qo00466d.
  2016 年研究论文：
  (1)
  Pengbo Zhang, Yuzhen Gao, Liangliang Zhang, Zhiqiang Li, Yan Liu, Guo Tang,* and Yufen Zhao. Copper-Catalyzed Cycloaddition between Secondary Phosphine Oxides and Alkynes: Synthesis of Benzophosphole Oxides. Adv. Synth. Catal., 2016, 358, 138.
  (2)
  Ju Wu, Yuzhen Gao, Liangliang Zhang, Weizhu Chen, Guo Tang,* and Yufen Zhao. Copper-Catalyzed Cycloaddition between Hydrogen Phosphonates and Activated Alkenes: Synthesis of Phosphonoisoquinolinediones. RSC Adv., 2016, 6, 303.
  (3)
  Yuzhen Gao, Guozhang Lu, Pengbo Zhang, Liangliang Zhang, Guo Tang,* and Yufen Zhao. A Cascade Phosphinoylation/Cyclization/Desulfonylation Process for the Synthesis of 3-Phosphinoylindoles. Org. Lett., 2016, 18, 1242.
  (4)
  Jian Xu, Liangliang Zhang, Xueqin Li, Yuzhen Gao, Guo Tang,* and Yufen Zhao. Phosphorothiolation of Aryl Boronic Acids Using P(O)H Compounds and Elemental Sulfur. Org. Lett., 2016, 18, 1266.
  (5)
  Liangliang Zhang, Su Chen,Yuzhen Gao, Pengbo Zhang, Yile Wu, Guo Tang,* and Yufen Zhao. tert-Butyl Hydroperoxide Mediated Cascade Synthesis of 3-Arylsulfonylquinolines. Org. Lett., 2016, 18, 1286.
  (6)
  Liangliang Zhang, Pengbo Zhang, Xueqin Li, Jian Xu,* Guo Tang,* and Yufen Zhao. Synthesis of S-Arylphosphorothioates by Copper-Catalyzed Phosphorothiolation of Diaryliodonium and Arenediazonium Salts. J. Org. Chem., 2016, 81, 5588.
  (7)
  Pengbo Zhang, Liangliang Zhang, Yuzhen Gao, Guo Tang,* and Yufen Zhao. Synthesis of Synthesis of 3-phosphinoylquinolines via a phosphinoylation-cyclization-aromatization process mediated by tert-butyl hydroperoxide RSC Adv., 2016, 6, 60922.
  (8)
  Su Chen,Pengbo Zhang,Wanyun Shu, Yuzhen Gao, Guo Tang,* and Yufen Zhao.Cascade Phosphinoylation/Cyclization/Isomerization Process for the Synthesis of 2Phosphinoyl9Hpyrrolo[1,2a]indoles. Org. Lett., 2016, 18, 5712.
  2015 年研究论文：
  (1)
  Jian Xu, Xueqin Li, Yuzhen Gao, Liangliang Zhang, Weizhu Chen, Hua Fang, Guo Tang* and Yufen Zhao.  Mn(III)-mediated phosphonation–azidation of alkenes: a facile synthesis of β-azidophosphonates. Chem. Commun., 2015, 51, 11240.
  (2)
  Yuzhen Gao, Jian Xu, Pengbo Zhang, Hua Fang, Guo Tang* and Yufen Zhao. Mn(OAc)3-mediated arylation–lactonization of alkenoic acids: synthesis of γ,γ-disubstituted butyrolactones. RSC Adv., 2015, 5, 36167.
  (3)
  Yuzhen Gao, Xueqin Li, Jian Xu, Yile Wu, Weizhu Chen, Guo Tang* and Yufen Zhao. Mn(OAc)3-mediated phosphonation–lactonization of alkenoic acids: synthesis of phosphono-γ-butyrolactones. Chem. Commun., 2015, 51, 1605.
  (4)
  Pengbo Zhang, Liangliang Zhang, Yuzhen Gao, Jian Xu, Hua Fang, Guo Tang* and Yufen Zhao. Copper-catalyzed tandem phosphination–decarboxylation– oxidation of alkynyl acids with H-phosphine oxides: a facile synthesis of β-ketophosphine oxides. Chem. Commun., 2015, 51, 7839.
  (5)
  Yuzhen Gao, Xueqin Li, Weizhu Chen, Guo Tang* and Yufen Zhao, Copper-catalyzed phosphonation–annulation approaches to the synthesis of  β-phosphonotetrahydrofurans involving C–P and C–O bonds formation. J. Org. Chem., 2015, 80, 11398.
  (6)
  Xueqin Li, Jian Xu, Yuzhen Gao, Hua Fang, Guo Tang* and Yufen Zhao, Cascade arylalkylation of activated alkenes: Synthesis of chloro- and cyano-containing oxindoles. J. Org. Chem., 2015, 80, 2621.
  2014 年研究论文：
  (1)
  Jian Xu, Pengbo Zhang, Xueqin Li, Yuzhen Gao, Ju Wu, Guo Tang* and Yufen Zhao. Bu4NI-Catalyzed phosphorylation of benzyl C-H bonds via a cross- dehydrogenative coupling (CDC) reaction. Adv. Synth. Catal., 2014, 356, 3331.
  (2)
  Pengbo Zhang, Jian Xu, Yuzhen Gao, Yiyin Chen, Guo Tang* and Yufen Zhao. Synthesis of diarylmethanes via Pd-catalyzed coupling of benzylic phosphates with arylsilanes. Synlett, 2014, 25, 2928.
  (3)
  Xueqin Li, Jian Xu, Pengbo Zhang, Yuzhen Gao, Ju Wu, Guo Tang* and Yufen Zhao. Copper-catalyed oxidative electrophilic carbofunctionalization of acrylamides for the synthesis of oxindoles. Synlett, 2014, 25, 2009.
  (4)
  Yuzhen Gao, Ju Wu, Jian Xu, Xuerui Wang, Guo Tang* and Yufen Zhao. Synthesis of 6-phenanthridinephosphonates via a Mn(OAc)3-mediated radical phosphonation and cyclization process. Asian J. Org. Chem., 2014, 3, 691.
  (5)
  Xunfu Xu, Hu Chen,* Yulei Wang, Yuxing Gao, Guo Tang* and Yufen Zhao. Catalyst-free synthesis of cycloalkenyl phosphonates. RSC Adv., 2014, 4, 14740.
  (6)
  Liu Liu, Ye Lv, Yile Wu, Xiang Gao, Zhiping Zeng, Yuxing Gao,* Guo Tang* and Yufen Zhao. Experimental and theoretical studies on nickel–zinc-catalyzed cross-coupling of gem-dibromoalkenes with P(O)–H compounds. RSC Adv., 2014, 4, 2322.
  (7)
  Yuzhen Gao, Ju Wu, Jian Xu, Pengbo Zhang, Guo Tang* and Yufen Zhao. Mn(OAc)3-mediated synthesis of β-hydroxyphosphonates from P(O)–H compounds and alkenes. RSC Adv., 2014, 4, 51776.
  2013 年研究论文：
  (1)
  Zengxiang Zhao, Wanhua Xue, Yuxing Gao, Guo Tang* and Yufen Zhao. Copper-catalyzed synthesis of α-hydroxy phosphonates from H-phosphonates and alcohols or ethers. Chem- Asian J., 2013, 8, 713.
  (2)
  Hu Chen,* Xunfu Xu, Liu Liu, Guo Tang* and Yufen Zhao. Phosphorus oxychloride as an efficient coupling reagent for the synthesis of esters, amides and peptides under mild conditions. RSC Adv., 2013, 3, 16247.
  (3)
  Yuzhen Gao, Zhongbin Huang, Rongqiang Zhuang, Jian Xu, Pengbo Zhang, Guo Tang* and Yufen Zhao. Direct transformation of amides into α-amino phosphonates via a reductive phosphination proces. Org. Lett., 2013, 15, 4214.
  (4)
  Jian Xu, Pengbo Zhang, Yuzhen Gao, Yiyin Chen, Guo Tang* and Yufen Zhao. Copper-catalyzed P-arylation via direct coupling of diaryliodonium salts with phosphorus nucleophiles at room temperature. J. Org. Chem., 2013, 78, 8176.
  2012年研究论文：
  (1)
  Wenjun Miao, Yuzhen Gao, Xueqin Li, Yuxing Gao, Guo Tang* and Yufen Zhao. Copper-catalyzed synthesis of alkylphosphonates from H-phosphonates and N-tosylhydrazones. Adv. Synth. Catal., 2012, 354, 2659.
  (2)
  Jian Xu, Rongqiang Zhuang, Lingling Bao, Guo Tang* and Yufen Zhao. KOH-mediated transition metal-free synthesis of imines from alcohols and amines. Green Chem., 2012, 14, 2384.
  (3)
  Jianwei Zhu, Wenjun Miao, Lingling Bao, Tao Ji, Guo Tang,* Pengxiang Xu and Yufen Zhao. A mild method for the cleavage of the 4-picolyloxy group with magnesium under neutral conditions. Sylett, 2012, 23, 142.
  2011年研究论文：
  (1)
  Guo Tang,* Chien-Hong Cheng.* Synthesis of a-Hydroxy Carboxylic Acids via a Nickel(II)- Catalyzed Hydrogen Transfer Process. Adv. Synth. Catal. 2011, 353, 1918.
  (2)
  Xing-Hua Zhang, Hui-Zhi Liu, Xiao-Mei Hu, Guo Tang,* Jun Zhu,* Yu-Fen Zhao. Ni(II)/Zn Catalyzed Reductive Coupling of Aryl Halides with Diphenylphosphine Oxide in Water. Org. Lett. 2011, 13, 3478.
  专利：
  (1)
  赵玉芬，唐果，周宁，胡利明，陈勇，丙－谷二肽合成方法，ZL 02123369.1, US 2005233977. 日本特许4942295, DE 10392821.
  (2)
  唐果，赵玉芬，许鹏翔，N(2)-L-丙氨酰－L-谷氨酰胺二肽合成方法， ZL 200510054083.
  (3)
  丙－谷二肽产品获得的原料药许可证:国药准字 H20041518; 注射液许可证: 国药准字 H20045404.