厦门大学化学化工学院有机化学研究所导师介绍:叶龙武
作者:聚创厦大考研网-小厦老师
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发布时间: 2018-08-23 15:13
微信号: H17720740258
叶龙武
教授、博士生导师
电话:0592-2185833
电子邮箱:longwuye@xmu.edu.cn
课题组网站:http://chem.xmu.edu.cn/group/lwye/index.html
个人简历:
博士后 (University of California at Santa Barbara,2009/05-2011/07)
博士后 (The Scripps Research Institute,2008/09-2009/05)
博士 (中科院上海有机所,2003/09-2008/07)
学士 (浙江大学化学系,1999/09-2003/07)
荣誉与获奖:
中科院院长优秀奖 (2008)
中科院优秀毕业生 (2008)
上海市自然科学一等奖 (2011)
福建省杰出青年科学基金 (2015)
Thieme Chemistry Journals Award (2016)
国家自然科学基金“优秀青年基金" (2016)
教育部青年长江学者 (2017)
研究兴趣:
有机合成方法学:过渡金属催化的选择性控制与多样性合成; 功能分子全合成:生物活性分子、天然产物及药物的合成。
近期主要代表论著:
27. W.-B. Shen, Q. Sun, L. Li, X. Liu, B. Zhou, J.-Z. Yan, X. Lu,* L.-W. Ye,* Divergent Synthesis of N-Heterocycles via Controllable Cyclization of Azido-Diynes Catalyzed by Copper and Gold, Nat. Commun. 2017, 8, 1748.
26. Z.-S. Wang, T.-D. Tan, C.-M. Wang, D.-Q. Yuan, T. Zhang, P. Zhu, C. Zhu,* J.-M. Zhou, L.-W. Ye,* Dual Gold/Photoredox-Catalyzed Bis-Arylative Cyclization of Chiral Homopropargyl Sulfonamides with Diazonium Salts: Rapid Access to Enantioenriched 2,3-Dihydropyrroles, Chem. Commun. 2017, 53, 6848.
25. L. Li, X.-M. Chen, Z.-S. Wang, B. Zhou, X. Liu, X. Lu,* L.-W. Ye,* Reversal of Regioselectivity in Catalytic Arene-Ynamide Cyclization: Direct Synthesis of Valuable Azepino[4,5-b]indoles and β–Carbolines and DFT Calculations, ACS Catal. 2017, 7, 4004.
24. B. Zhou, L. Li, X.-Q. Zhu, J.-Z. Yan, Y.-L. Guo, L.-W. Ye*, Yttrium-Catalyzed Tandem Intramolecular Hydroalkoxylation/Claisen Rearrangement: Efficient Synthesis of Medium-Sized Lactams, Angew. Chem. Int. Ed. 2017, 56, 4015.
23. W.-B. Shen,? X.-Y. Xiao,? Q. Sun, B. Zhou, X.-Q. Zhu, J.-Z. Yan, X. Lu,* L.-W. Ye*, (?Shen and Xiao have an equal contribution to this paper) Highly Site-Selective Formal [5+2] and [4+2] Annulations of Isoxazoles with Heterosubstituted Alkynes by Platinum Catalysis: Rapid Access to Functionalized 1,3-Oxazepines and 2,5-Dihydropyridines, Angew. Chem. Int. Ed. 2017, 56, 605.
22. F. Pan,? X.-L. Li,? X.-M. Chen, C. Shu, P.-P. Ruan, C.-H. Shen, X. Lu,* L.-W. Ye*, (?Pan and Li have an equal contribution to this paper) Catalytic Ynamide Oxidation Strategy for the Preparation of α-Functionalized Amides, ACS Catal. 2016, 6, 6055.
21. Y.-F. Yu, C. Shu, T.-D. Tan, L. Li, S. Rafique, L.-W. Ye,* Synthesis of Enantioenriched Pyrrolidines via Gold-Catalyzed Tandem Cycloisomerization/Hydrogenation of Chiral Homopropargyl Sulfonamides, Org. Lett. 2016, 18, 5178. (Highlighted by: Synfacts, 2017, 13, 51)
20. C. Shu, C.-H. Shen, Y.-H. Wang, L. Li, T. Li, X. Lu,* L.-W. Ye,* Synthesis of 2-Aza-1,3-butadienes through Gold-Catalyzed Intermolecular Ynamide Amination/C-H Functionalization, Org. Lett. 2016, 18, 4630.
19. C. Shu, Y.-H. Wang, C.-H. Shen, P.-P. Ruan, X. Lu,* L.-W. Ye,* Gold-Catalyzed Intermolecular Ynamide Amination-Initiated Aza-Nazarov Cyclization: Access to Functionalized 2-Aminopyrroles, Org. Lett. 2016, 18, 3254. (Highlighted by: Organic Chemistry Portal)
18. C. Shu, L. Li, C.-H. Shen, P.-P. Ruan, C.-Y. Liu, L.-W. Ye,* Gold-Catalyzed Tandem Cycloisomerization/Halogenation of Chiral Homopropargyl Sulfonamides, Chem. Eur. J. 2016, 22, 2282. (selected as a frontispiece and hot paper)
17. C. Shu, Y.-H. Wang, B. Zhou, X.-L. Li, Y.-F. Ping, X. Lu,* L.-W. Ye,* Generation of α-Imino Gold Carbenes through Gold-Catalyzed Intermolecular Reaction of Azides with Ynamides, J. Am. Chem. Soc. 2015, 137, 9567. (Highlighted by JACS Homepage)
16. L. Li,? B. Zhou,? Y.-H. Wang, C. Shu, Y.-F. Pan, X. Lu,* L.-W. Ye,* (?Li and Zhou have an equal contribution to this paper) Zinc-Catalyzed Tandem Alkyne Oxidation/C?H Functionalization: Highly Site-Selective Synthesis of Versatile Isoquinolones and β-Carbolines, Angew. Chem. Int. Ed. 2015, 54, 8245. (Featured in Chin. J. Org. Chem. 2015, 35, 2019 & invited as SYNPACTS article)
15. A.-H. Zhou, Q. He, C. Shu, Y.-F. Yu, S. Liu, T. Zhao, W. Zhang, X. Lu,* L.-W. Ye,* Atom-Economic Generation of Gold Carbenes: Gold-Catalyzed Formal [3+2] Cycloaddition between Ynamides and Isoxazoles, Chem. Sci. 2015, 6, 1265.
14. Y.-F. Yu, C. Shu, B. Zhou, J.-Q. Li, J.-M. Zhou, L.-W. Ye,* Efficient and Practical Synthesis of Enantioenriched 2,3-Dihydropyrroles through Gold-Catalyzed Anti-Markovnikov Hydroamination of Chiral Homopropargyl Sulfonamides, Chem. Commun. 2015, 51, 2126. (Highlighted by: Organic Chemistry Portal)
13. A.-H. Zhou, F. Pan, C. Zhu,* L.-W. Ye,* Recent Progress towards Transition Metal-Catalyzed Synthesis of Fluorenes, Chem. Eur. J. 2015, 21, 10278. (invited review paper)
12. L. Li,? C. Shu,? B. Zhou, Y.-F. Yu, X.-Y. Xiao, L.-W. Ye,* (?Li and Shu have an equal contribution to this paper) Generation of Gold Carbenes in Water: Efficient Intermolecular Trapping of the α-Oxo Gold Carbenoids by Indoles and Anilines, Chem. Sci. 2014, 5, 4057.
11. F. Pan, S. Liu, C. Shu, R.-K. Lin, Y.-F. Yu, J.-M. Zhou, L.-W. Ye,* Gold-Catalyzed Intermolecular Oxidation of o-Alkynylbiaryls: An Easy and Practical Access to Functionalized Fluorenes, Chem. Commun. 2014, 50, 10726.
10. C. Shu, L. Li, X.-Y. Xiao, Y.-F. Yu, Y.-F. Ping, J.-M. Zhou, L.-W. Ye,* Flexible and Practical Synthesis of 3-Oxyindoles through Gold-Catalyzed Intermolecular Oxidation of o-Ethynylanilines, Chem. Commun. 2014, 50, 8689.
9. C. Shu, L. Li, Y.-F. Yu, S. Jiang, L.-W. Ye,* Gold-Catalyzed Intermolecular Oxidation of Chiral Homopropargyl Sulfonamides: A Reliable Access to Enantioenriched Pyrrolidin-3-ones, Chem. Commun. 2014, 50, 2522.
8. C. Shu, C.-B. Chen, W.-X. Chen, L.-W. Ye,* Flexible and Practical Synthesis of Anthracenes through Gold-Catalyzed Cyclization of o-Alkynyldiarylmethanes, Org. Lett. 2013, 15, 5542. (Highlighted by: Synfacts, 2014, 10, 30)
7. C. Shu, M.-Q. Liu, Y.-Z. Sun, L.-W. Ye,* Efficient Synthesis of γ-Lactones via Gold-Catalyzed Tandem Cycloisomerization/Oxidation, Org. Lett. 2012, 14, 4958. (Highlighted by: Organic Chemistry Portal)
6. L. Ye, Y. Wang, D. Aue, L. Zhang,* Experimental and Computational Evidence for Gold Vinylidenes: Generation from Terminal Alkynes via a Bifurcation Pathway and Facile C?H Insertions, J. Am. Chem. Soc. 2012, 134, 31.
5. L. Ye, W. He, L. Zhang,* A Flexible and Stereoselective Synthesis of Azetidine-3-one via A Key Gold-Catalyzed Intermolecular Alkyne Oxidation, Angew. Chem. Int. Ed. 2011, 50, 3236. (For a highlight, see: Synfacts, 2011, 6, 630)
4. L. Ye, W. He, L. Zhang,* Gold-Catalyzed One-Step Practical Synthesis of Oxetan-3-ones from Readily Available Propargylic Alcohols, J. Am. Chem. Soc. 2010, 132, 8550.
3. L. Ye, L. Cui, G. Zhang, L. Zhang,* Alkynes as Equivalents of α-Diazo Ketones in Generating α-Oxo Metal Carbenes: A Gold-Catalyzed Expedient Synthesis of Dihydrofuran-3-ones, J. Am. Chem. Soc. 2010, 132, 3258.
2. L.-W. Ye, J. Zhou, Y. Tang,* Phosphine-Triggered Synthesis of Functionalized Cyclic Compounds, Chem. Soc. Rev. 2008, 37, 1140.
1. L.-W. Ye, X.-L. Sun, Q.-G. Wang, Y. Tang,* Phosphine-Catalyzed Intramolecular Formal [3+2] Cycloaddition for Highly Diastereoselective Synthesis of Bicyclo[n.3.0] Compounds, Angew. Chem. Int. Ed. 2007, 46, 5951. (For a highlight, see: Synfacts, 2007, 10, 1101)
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